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Anti -Hsp47 Rabbit pAb

貨號:GB111425

品牌:Servicebio

價格:¥650

規格: 100 μl

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Product Information

 

Description Hsp47 rabbit polyclonal
Protein full name Serpin H1
Synonyms 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serine protease inhibitor J6, Serpinh1, Cbp1, Hsp47
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse Hsp47
Isotype IgG
Purity Affinity purification
Subcellular location Cytoplasm
Uniprot ID P50454, P19324

 


 

Applications

 

Applications Species Dilution Positive Tissue
IHC Human, Mouse 1: 1000-1: 2000 colon cancer, ovary cancer
IF Human, Mouse 1: 500-1: 1000 colon cancer, skin, placenta

 


 

Background

 

Hsp47, also known as colligin and gp46, is an ER-resident collagen-specific stress glycoprotein involved in the synthesis and assembly of varoius collagens as a molecular chaperone. Hsp47 is a member of the serpin superfamily, but localizes to the ER via binding of its C-terminal RDEL sequence to KDEL receptors in the ER. Hsp47 binds procollagen co-translationally as it enters the ER, and dissociates prior to its secretion.

     


 

Images

 




Immunohistochemistry analysis of paraffin-embedded human colon cancer using Hsp47 (GB111425) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded human ovary cancer using
Hsp47 (GB111425) at dilution of 1: 2000

Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using Hsp47 (GB111425) at dilution of 1: 800

Immunofluorescent analysis of paraformaldehyde-fixed mouse skin using
Hsp47 (GB111425) at dilution of 1: 800

Immunofluorescent analysis of paraformaldehyde-fixed mouse placenta using Hsp47 (GB111425) at dilution of 1: 800

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

 

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